*trainee names underlined


2020 - 2021


Olivier JF, Fodil N, Al Habyan S, Gopal A, Artusa P, Mandl JN, McCaffrey L, Gros P. (2020) "CCDC88B is required for mobility and inflammatory functions of dendritic cells". J Leukoc Biol: 1-16


Wortel IMN, Kesmir C, de Boer RJ, Mandl JN, Textor J. (2020) "Is T cell Negative Selection a Learning Algorithmn?" Cells 9(3): pii E690

> For a unique read into the paper, check out Inge Wortel's blog post! 


Gentile ME, Li Y, Robertson A, Shah K, Fontes G, Kaufmann E, Polese B, Khan N, Parisien M, Munter HM, Mandl JN, Diatchenko L, Divangahi M, King IL. (2020) "NK Cells Recruitment limits tissue damage during an enteric helminth infection". Mucosal Immunology 13(2): 357-370.


2018 -2019


Sood A, Lebel MÈ, Fournier M, Rogers DMandl JN, Melichar HJ. (2019) "Differential interferongamma production potential among naive CD4+ T cells exists prior to antigen encounter". Immunology and Cell Biology 97(10): 931-940. 


Yuki, K.E., Marei, H., Fiskin, E., Eva, M.M., Gopal, A.A., Schwartzentruber, J.A., Majewski, J., Cellier, M., Mandl, J.N., Vidal, S.M., Malo, D., and Dikic, I. “CYRI1/FAM49B Negatively Regulates RAC1-driven Cytoskeletal Remodelling and Protects Against Bacterial Infection". Nat Microbiol 4(9): 1516-1531. doi:10.1101/238733


Tong, A.A., Forestell, B., Murphy, D.V., Nair, A., Allen, F., Myers, J., Klauschen, F., Shen, C., Gopal, A.A., Huang, A.Y., Mandl, J.N. (2019) "Regulatory T cells differ from conventional CD4+ T cells in their recirculatory behavior and lymph node transit times." Immunol Cell Biol. doi: 10.111.imcb.12276.


Mandl, J.N., Schneider, C., Schneider, D.S., and Baker, M.L. (2018) “Going to bat(s) for studies of disease tolerance.” Frontiers in Immunology 9:2112.


2016 -2017


Dong, M., Artusa, P., Kelly, S.A., Fournier, M., Baldwin, T.A., Mandl, J.N., and Melichar, H.J. (2017) “Alterations in the thymic selection threshold skew the self-reactivity of the T cell receptor repertoire in neonates.” Journal of Immunology. 199(3):965-973.


Vrisekoop, N., Artusa P., Monteiro, J.P., and Mandl, J.N. (2017) “Weakly self-reactive T cell clones can homeostatically expand when present at low numbers.” Eur J Immunol 47(1):68-73.


Textor, J., Mandl, J.N., and de Boer, R.J. (2016) “The reticular cell network: a robust backbone for immune responses.” PLos Biology 14(10):e2000827



Lippens, C., Duraes, F. V., Guery, L., Dubrot, J., Brighouse, D., Lacroix, M., Magali, I., Aubry-Lachainaye, J., Reith, W., Mandl, J.N., and Hugues, S. (2016) “IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity.” Journal of Autoimmunity 75:39-49.


2014 -2015


Mandl, J.N., and Feinberg, M.B. (2015) “Robust and sustained immune activation in human Ebola virus infection.” Proc. Natl. Acad. Sci. USA, 112(15):4518-9. (Commentary).


Mandl, J.N., Barreiro, L., Epstein, J., Daszak, P., Ahmed, R., Virgin, H., and Feinberg, M.B. (2015) “Reservoir host immune responses to emerging zoonotic viruses.” Cell, 160 (1-2):20-35.


Zhang, Q., Dove, C., Strauss-Albee, D., Garcia, J., Mandl, J.N., Grodick, R., Chandler-Brown, D., Jing, H., Kim, E., Lenardo, T.E., Matthews, H.F., Freeman, A.F., Cornall, R.J., Germain, R.N., Mueller, S.N., and Su, H. (2014)  “DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.” Journal of Experimental Medicine, 211(13):2549-66.


Textor, J., Hendrickson, S.E., Mandl, J.N., von Andrian, U.H., Westermann, J., de Boer, R.J., and Beltman, J.B. (2014) “Random Migration and Signal Integration Promote Rapid and Robust T cell Recruitment.” PLoS Computational Biology 10(8): e1003752.


Vrisekoop, N., Monteiro, J.P., Mandl, J.N., and Germain, R.N. (2014) “Revisiting thymic positive selection and the mature T cell repertoire for antigen.” Immunity 41(2):181-190.


Mandl, J.N. and Germain, R.N. (2014) “Focusing in on T cell cross-reactivity.” Cell. 157(5): 1006-1008.



Mandl, J.N., Torabi-Parizi, P., and Germain, R.N. (2014) “Visualization and dynamic analysis of host-pathogen interactions.” Curr. Opin. Immunol. 29:8-15.


Bouma, H.R., Mandl, J.N., Strijkstra, A.M., Boerema, A.S., Kok, J.W., van Dam, A., Ijzerman, A., Kroese, F.G., Henning, R.H. (2013) “5’AMP impacts lymphocyte recirculation through activation of A2B receptors.” J. Leukocyte Biology, 94(1):89-98.


2013 & earlier


Mandl, J.N., Monteiro, J.P., Vrisekoop, N., and Germain, R.N. (2013) “T cell positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens.” Immunity 38(2):263-74.


Mandl, J.N., Liou, R., Klauschen, F., Vrisekoop, N., Monteiro, J.P., Yates, A.J., Huang, A.Y., and Germain, R.N. (2012) “Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naïve CD4 and CD8 T cells.” Proc Natl Acad Sci USA 109(44):18036-41.


Meteyer, C.U., Barber, D., Mandl, J.N. (2012) “Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome.” Virulence 3(7).


Lee, M., Mandl, J.N., Germain, R.N., and Yates, A.J. (2012) “The race for the prize – T cell trafficking strategies”. Blood 120(7):1432-8.


Mandl, J.N., Akondy, R., Lawson, B., Kozyr, N., Staprans, S.I., Ahmed, R., and Feinberg, M.B. (2011) “Distinctive TLR7 signalling, type I interferon production and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host.” J. Immunology 186(11):6406-16.


Vrisekoop, N., Mandl, J.N., and Germain, R.N. (2009) “Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.” Journal of Biology 8(10):91


Mandl, J.N., Barry, A.P., Vanderford, T.H., Kozyr, N., Chavan, R., Klucking, S., Barrat, F.J., Coffman, R.L., Staprans, S.I., and Feinberg, M.B. (2008) “DIvergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.” Nature Medicine 14 (10): 1077–1087.